Profile

  • History of successful work in interdisciplinary & intercultural environments.
  • Motivated to leverage deep understanding of machine learning algorithms and workflows to create a positive impact.
  • Passion for creating machine learning applications, ensuring the highest standards of quality, as well as scientific rigor.
  • Creative, collaborative, and innovation focused.

Experience

PhD Student

Aug 2020 - Dec 2025
CompCancer Graduate School, Charité Berlin, MDC Berlin, Humboldt University Berlin

Data-Efficient Deep Learning for Biomarker Prediction in Angiosarcoma

  • Development of an open-source pipeline (PEERCE) leveraging pre-trained generalist models and fine-tuned segmentation/classification networks for PD-L1 Tumor Proportion Score (TPS) prediction.
  • Validated the tool’s utility to improve pathologist concordance. Published in Journal of Pathology Informatics.

Unsupervised Domain Adaptation for Generalist Cell Segmentation Models

  • Design and implementation of SelfAdapt, a source-free Unsupervised Domain Adaptation (UDA) framework.
  • Introduced and evaluated novel label-free early stopping criteria. Delivered the method as an open-source extension to the Cellpose ecosystem. Published in ICCV BIC.

PhenoBench: A Comprehensive Benchmark for Foundation Model Evaluation in Pathology

  • Development of a benchmarking framework to evaluate the generalization of pathology foundation models under technical and medical domain shifts. Implemented in Python using PyTorch. Published in MICCAI.

Machine Learning Engineer

Jan 2021 - Oct 2023
Subtle Medical

Deep Learning for Tau PET Prediction in Alzheimer’s Disease

  • Led a collaboration with Eli Lilly to develop an AI framework for predicting future Tau accumulation from baseline scans + clinical/genetic covariates (deep CNN feature extraction + tree-based models).
  • Demonstrated superior performance in identifying rapid progressors, optimizing patient selection strategies.

Visiting Research Scholar

Oct 2018 - Jul 2020
Stanford University

Systematic benchmark to analyze CNN performance as well as relative generalization capabilities

  • Use of simulated static patterns to assess CNN performance. CNN training and testing coded in Python using PyTorch. Experiments were run on a Stanford high performance cluster, as well as Google Cloud. Published.

Deep Learning to Predict Standardized Uptake Value Ratio and Amyloid Status on 18F-florbetapir

  • Creation of deep learning pre-processing pipeline and CNN training on compute cluster. Published.

Predicting Future Imaging Biomarkers with Machine Learning: An Amyloid Study

  • Employment of CNNs and gradient boosted decision tree to predict development of standardized uptake value ratio. Method was patented. Published.

Deep Learning Exchange

Jan 2018 - Jun 2018
Robert Bosch LLC

Lead development and deployment of service for visual detection of erroneous production parts.

  • Combined neural network classification with low-latency algorithmic image segmentation to identify manufacturing errors in production parts. Researched ways to reduce generalization error.

Scientific Programmer

Jun 2017 - Dec 2017
Acrai

Implementation and benchmarking of object detecting CNNs to identify weeds in farming environments.

  • Established new data preprocessing pipeline and modified TensorFlow Object Detection API for enhanced validation.

Machine Learning Research Intern

Feb 2017 - Apr 2017
Robert Bosch LLC

Use of big industry-specific dataset to create pretrained CNN weights for transfer learning. Resulting CNN presented to Bosch CEO at research presentation session.

  • Modification of C++ Caffe Deep Learning Framework to allow for 4-channel CNN input. Implementation of improved data pre-processing pipeline.

Patents & Certifications

Systems and Methods for Improved Prognostics in Medical Imaging

2022
US Patent Office (17647950)

Co-inventor with Greg Zaharchuk. Methods for predicting biomarker progression in medical imaging to identify fast/moderate/slow progressors for clinical trial enrollment.

Machine Learning

Stanford University & Coursera

Stanford University Machine Learning Certificate via Coursera

Open Source Projects

Key open-source contributions in computational pathology and machine learning.

PEERCE - Pipeline for PD-L1 Tumor Proportion Score prediction using foundation models and fine-tuned segmentation networks.
SelfAdapt - Source-free Unsupervised Domain Adaptation framework for cell segmentation, extending the Cellpose ecosystem.
Pathology Foundation Model Benchmark - Comprehensive benchmarking framework to evaluate pathology foundation models under domain shifts.

Publications

Selected peer-reviewed publications in machine learning, medical imaging, and computational pathology.

  • PD-L1 Expression Assessment in Angiosarcoma Improves with Artificial Intelligence Support
  • F.H. Reith, A. Jarosch, J.P. Albrecht, et al.
    Journal of Pathology Informatics (2025)
  • SelfAdapt: Unsupervised Domain Adaptation of Cell Segmentation Models
  • F.H. Reith, J. Franzen, D. Palli, J.L. Rumberger, D. Kainmueller
    ICCV Workshop on Bioimage Computing (2025)
  • PathoCellBench: A Comprehensive Benchmark for Cell Phenotyping
  • F.H. Reith, J. Lüscher, N. Koreuber, J. Franzen, et al.
    MICCAI (2025)
  • Predicting Future Amyloid Biomarkers in Dementia Patients with Machine Learning
  • F.H. Reith, E.C. Mormino, G. Zaharchuk
    Alzheimer's & Dementia (2021)
  • Application of Deep Learning to Predict Standardized Uptake Value Ratio and Amyloid Status on 18F-Florbetapir PET
  • F.H. Reith, M.E. Koran, G. Davidzon, G. Zaharchuk
    American Journal of Neuroradiology (2020)

    Skills & Proficiency

    Python

    PyTorch

    HuggingFace Transformers

    OpenCV

    Git & Linux

    scikit-learn

    Docker

    SQL